Markus G. Grütter : rechercher sur Z-Library

Tummers, Marcia, KvÃ¦rner, Kari, Sampietro-Colom, Laura, Siebert, Markus, Krahn, Murray, Melien, Ãyvind, Hamerlijnck, Dominique, Abrishami, Payam, Grutters, Janneke

Année:

2013

Langue:

english

Fichier:

PDF, 3.22 MB

english, 2013

On the integration of early health technology assessment in the innovation process: reflections from five stakeholders

Journal:

International Journal of Technology Assessment in Health Care

Année:

2020

Fichier:

PDF, 149 KB

2020

Amino acid dimorphism and parasite immune evasion: cellular immune responses to a promiscuous epitope of Plasmodium falciparum merozoite surface protein 1 displaying dimorphic amino acid polymorphism are highly constrained

Claudia A. Daubenberger, Beatrice Nickel, Carlo Ciatto, Markus G. Grütter, Friederike Pöltl-Frank, Laura Rossi, Uwe Siegler, John Robinson, Oscar Kashala, Manuel Elkin Patarroyo, Gerd Pluschke

Journal:

European Journal of Immunology

Année:

2002

Langue:

english

Fichier:

PDF, 212 KB

english, 2002

Mutations and protein stability

John A. Schellman, Margaret Lindorfer, Richard Hawkes, Markus Grutter

Journal:

Biopolymers

Année:

1981

Langue:

english

Fichier:

PDF, 611 KB

english, 1981

Structure–Activity Studies in a Family of β-Hairpin Protein Epitope Mimetic Inhibitors of the p53–HDM2 Protein–Protein Interaction

Rudi Fasan, Ricardo L. A. Dias, Kerstin Moehle, Oliver Zerbe, Daniel Obrecht, Peer R. E. Mittl, Markus G. Grütter, John A. Robinson

Journal:

ChemBioChem

Année:

2006

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2006

Isolation of a Small-Molecule Inhibitor of the Antiapoptotic Protein Bcl-xL from a DNA-Encoded Chemical Library

Samu Melkko, Luca Mannocci, Christoph E. Dumelin, Alessandra Villa, Roberto Sommavilla, Yixin Zhang, Markus G. Grütter, Nadine Keller, Lutz Jermutus, Ronald H. Jackson, Jörg Scheuermann, Dario Neri

Journal:

ChemMedChem

Année:

2010

Langue:

english

Fichier:

PDF, 916 KB

english, 2010

Structural and functional insights into the assembly of type 1 pili from Escherichia coli

Guido Capitani, Oliv Eidam, Rudi Glockshuber, Markus G. Grütter

Journal:

Microbes and Infection

Année:

2006

Langue:

english

Fichier:

PDF, 443 KB

english, 2006

HIV-1 protease inhibition potential of functionalized polyoxometalates

Andreas Flütsch, Thilo Schroeder, Markus G. Grütter, Greta R. Patzke

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 577 KB

english, 2011

Selective and Sensitive Monitoring of Caspase-1 Activity by a Novel Bioluminescent Activity-Based Probe

Maik Kindermann, Heidi Roschitzki-Voser, Dejan Caglič, Urška Repnik, Catherine Miniejew, Peer R.E. Mittl, Gregor Kosec, Markus G. Grütter, Boris Turk, K. Ulrich Wendt

Journal:

Chemistry & Biology

Année:

2010

Langue:

english

Fichier:

PDF, 521 KB

english, 2010

Structure and zymogen activation of caspases

Mrudula Donepudi, Markus G Grütter

Journal:

Biophysical Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2002

Optimisation of the P2 pharmacophore in a series of thrombin inhibitors: Ion-dipole interactions with lysine 60G

John Ambler, Lyndon Brown, Xiao-Ling Cockcroft, Markus Grütter, Judy Hayler, Diana Janus, Darryl Jones, Peter Kane, Keith Menear, John Priestle, Garrick Smith, Mark Talbot, Clive V Walker, Bernard Wat

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 284 KB

english, 1999

Structural genomics: opportunities and challenges

Peer R.E Mittl, Markus G Grütter

Journal:

Current Opinion in Chemical Biology

Année:

2001

Langue:

english

Fichier:

PDF, 72 KB

english, 2001

Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding

Guido Capitani, Andrew C. Eliot, Heinz Gut, Radii M. Khomutov, Jack F. Kirsch, Markus G. Grütter

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2003

Langue:

english

Fichier:

PDF, 707 KB

english, 2003

Changes in interactions in complexes of hirudin derivatives and human α-thrombin due to different crystal forms

John P. Priestle, Joseph Rahuel, Hans Rink, Michael Tones, Markus G. Grütter

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1993

The crystal structure of TGF-β3 and comparison to TGF-β2: Implications for receptor binding

Peer R. E. Mittl, John P. Priestle, David A. Cox, Gary Mcmaster, Nico Cerletti, Markus G. Grütter

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 5.58 MB

english, 1996

Recombinant hirustasin: Production in yeast, crystallization, and interaction with serine proteases

Stefania Di Marco, Gabriele Fendrich, Rene Knecht, Andre Strauss, Gabriele Pohlig, Jutta Heim, John P. Priestle, Markus G. Grütter, Christian P. Sommerhoff

Journal:

Florence Bourquin, Guido Capitani, Markus Gerhard Grütter

Année:

1997

Langue:

english

Fichier:

PDF, 3.71 MB

english, 1997

PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2011

Structural model of human GAD65: Prediction and interpretation of biochemical and immunogenic features

Guido Capitani, Daniela De Biase, Heinz Gut, Shaheen Ahmed, Markus G. Grütter

Journal:

H. Kaspar Binz, Andreas Kohl, Andreas Plückthun, Markus G. Grütter

Année:

2005

Langue:

english

Fichier:

PDF, 891 KB

english, 2005

Crystal structure of a consensus-designed ankyrin repeat protein: Implications for stability

Journal:

Haibo Yu, Andreas Kohl, H. Kaspar Binz, Andreas Plückthun, Markus G. Grütter, Wilfred F. van Gunsteren

Année:

2006

Langue:

english

Fichier:

PDF, 706 KB

english, 2006

Molecular dynamics study of the stabilities of consensus designed ankyrin repeat proteins

Journal:

Guido Capitani, Oliv Eidam, Markus G. Grütter

Année:

2006

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2006

Evidence for a novel domain of bacterial outer membrane ushers

Journal:

Martin A. Schärer, Markus G. Grütter, Guido Capitani

Année:

2006

Langue:

english

Fichier:

PDF, 871 KB

english, 2006

CRK: An evolutionary approach for distinguishing biologically relevant interfaces from crystal contacts

Journal:

Markus G. Grütter, Richard B. Hawkes

Année:

2010

Langue:

english

Fichier:

PDF, 149 KB

english, 2010

Mutations and the conformational stability of globular proteins

Journal:

Naturwissenschaften (The Science of Nature)

Année:

1983

Langue:

english

Fichier:

PDF, 513 KB

english, 1983

Molecular basis of thermostability in the lysozyme from bacteriophage T4

GRÜTTER, MARKUS G., HAWKES, RICHARD B., MATTHEWS, BRIAN W.

Journal:

Nature

Année:

1979

Fichier:

PDF, 310 KB

1979

An unusual feature revealed by the crystal structure at 2.2 Å resolution of human transforming growth fact or-β2

Schlunegger, Michael P., Grütter, Markus G.

Journal:

Nature

Année:

1992

Fichier:

PDF, 643 KB

1992

10.1038/88527

Dunn, Bruce E., Grütter, Markus G.

Journal:

Natural Structural Biology

Année:

2001

Langue:

english

Fichier:

PDF, 52 KB

english, 2001

High-affinity binders selected from designed ankyrin repeat protein libraries

Binz, H Kaspar, Amstutz, Patrick, Kohl, Andreas, Stumpp, Michael T, Briand, Christophe, Forrer, Patrik, Grütter, Markus G, Plückthun, Andreas

Journal:

Nature Biotechnology

Année:

2004

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2004

Structural basis for specificity of GRB2-SH2 revealed by a novel ligand binding mode

Rahuel, Joseph, Gay, Brigitte, Erdmann, Dirk, Strauss, André, García-Echeverría, Carlos, Furet, Pascal, Caravatti, Giorgio, Fretz, Heinz, Schoepfer, Joseph, Grütter, Markus G.

Journal:

Natural Structural Biology

Année:

1996

Fichier:

PDF, 551 KB

1996

Structural basis and kinetics of inter- and intramolecular disulfide exchange in the redox catalyst DsbD

Rozhkova, Anna, Stirnimann, Christian U, Frei, Patrick, Grauschopf, Ulla, Brunisholz, René, Grütter, Markus G, Capitani, Guido, Glockshuber, Rudi

Journal:

The EMBO Journal

Année:

2004

Langue:

english

Fichier:

PDF, 425 KB

english, 2004

Structural basis of chaperone–subunit complex recognition by the type 1 pilus assembly platform FimD

Nishiyama, Mireille, Horst, Reto, Eidam, Oliv, Herrmann, Torsten, Ignatov, Oleksandr, Vetsch, Michael, Bettendorff, Pascal, Jelesarov, Ilian, Grütter, Markus G, Wüthrich, Kurt

Journal:

The EMBO Journal

Année:

2005

Langue:

english

Fichier:

PDF, 931 KB

english, 2005

Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB

Gut, Heinz, Pennacchietti, Eugenia, John, Robert A, Bossa, Francesco, Capitani, Guido, De Biase, Daniela, Grütter, Markus G

Journal:

The EMBO Journal

Année:

2006

Langue:

english

Fichier:

PDF, 366 KB

english, 2006

Quality control of disulfide bond formation in pilus subunits by the chaperone FimC

Crespo, Maria D, Puorger, Chasper, Schärer, Martin A, Eidam, Oliv, Grütter, Markus G, Capitani, Guido, Glockshuber, Rudi

Journal:

Nature Chemical Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2012

Structure-based optimization of designed Armadillo-repeat proteins

Chaithanya Madhurantakam, Gautham Varadamsetty, Markus G. Grütter, Andreas Plückthun, Peer R.E. Mittl

Journal:

Johann Berger, Roger M. Burnett, Richard M. Franklin, Markus Grütter

Année:

2012

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2012

Small angle X-ray scattering studies on adenovirus type 2 hexon

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure

Année:

1978

Langue:

english

Fichier:

PDF, 442 KB

english, 1978

Crystal structure of the ternary FimC–FimFt–FimDN complex indicates conserved pilus chaperone–subunit complex recognition by the usher FimD

Oliv Eidam, Florian S.N. Dworkowski, Rudi Glockshuber, Markus G. Grütter, Guido Capitani

Journal:

FEBS Letters

Année:

2008

Langue:

english

Fichier:

PDF, 536 KB

english, 2008

Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy

Martin A. Schärer, Andrew C. Eliot, Markus G. Grütter, Guido Capitani

Journal:

FEBS Letters

Année:

2011

Langue:

english

Fichier:

PDF, 469 KB

english, 2011

Opportunities for structure-based design of protease-directed drugs

Peer RE Mittl, Markus G Grütter

Journal:

Current Opinion in Structural Biology

Année:

2006

Langue:

english

Fichier:

PDF, 1012 KB

english, 2006

NMR Structure of the Apoptosis- and Inflammation-Related NALP1 Pyrin Domain

Sebastian Hiller, Andreas Kohl, Francesco Fiorito, Torsten Herrmann, Gerhard Wider, Jürg Tschopp, Markus G Grütter, Kurt Wüthrich

Journal:

Christian U. Stirnimann, Anna Rozhkova, Ulla Grauschopf, Markus G. Grütter, Rudi Glockshuber, Guido Capitani

Année:

2003

Langue:

english

Fichier:

PDF, 328 KB

english, 2003

Structural Basis and Kinetics of DsbD-Dependent Cytochrome c Maturation

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 489 KB

english, 2005

Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein

Andreas Kohl, Patrick Amstutz, Petra Parizek, H. Kaspar Binz, Christophe Briand, Guido Capitani, Patrik Forrer, Andreas Plückthun, Markus G. Grütter

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 702 KB

english, 2005

Structure of the Mammalian NOS Regulator Dimethylarginine Dimethylaminohydrolase: A Basis for the Design of Specific Inhibitors

Daniel Frey, Oliver Braun, Christophe Briand, Milan Vašák, Markus G. Grütter

Journal:

Andreas Schweizer, Heidi Roschitzki-Voser, Patrick Amstutz, Christophe Briand, Maya Gulotti-Georgieva, Eva Prenosil, H. Kaspar Binz, Guido Capitani, Antonio Baici, Andreas Plückthun, Markus G. Grütter

Année:

2006

Langue:

english

Fichier:

PDF, 873 KB

english, 2006

Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2007

Infinite Kinetic Stability against Dissociation of Supramolecular Protein Complexes through Donor Strand Complementation

Chasper Puorger, Oliv Eidam, Guido Capitani, Denis Erilov, Markus G. Grütter, Rudi Glockshuber

Journal:

Gaby Sennhauser, Markus G. Grütter

Année:

2008

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2008

Chaperone-Assisted Crystallography with DARPins

Journal:

Nadine Keller, Jiří Mareš, Oliver Zerbe, Markus G. Grütter

Année:

2008

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2008

Structural and Biochemical Studies on Procaspase-8: New Insights on Initiator Caspase Activation

Journal:

Florence Bourquin, Howard Riezman, Guido Capitani, Markus G. Grütter

Année:

2009

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2009

Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2010

Proteinase inhibitors: another new fold

Markus G Grütter

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 230 KB

english, 1994

A new structural class of serine protease inhibitors revealed by the structure of the hirustasin–kallikrein complex

Peer RE Mittl, Stefania Di Marco, Gabriele Fendrich, Gabriele Pohlig, Jutta Heim, Christian Sommerhoff, Hans Fritz, John P Priestle, Markus G Grütter

Journal:

Isabel Usón, George M Sheldrick, Eric de La Fortelle, Gerard Bricogne, Stefania Di Marco, John P Priestle, Markus G Grütter, Peer RE Mittl

Année:

1997

Langue:

english

Fichier:

PDF, 767 KB

english, 1997

The 1.2 Å crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors

Journal: